Giant loops of DNA carried by bacteria in our mouth may have a beneficial impact on our oral health and our immune systems, potentially reducing the risk of certain cancers. Named 'Inocles', the ...

When you buy through links on our articles, Future and its syndication partners may earn a commission. Newfound bits of DNA in the human oral microbiome may be linked to the function of the immune ...

Extrachromosomal DNAs (ecDNAs) are circular DNA structures located in the nuclei of cells outside chromosomes. They were originally discovered in chromosome spreads of cells obtained from embryonal ...

A schematic describing what Inocles do and where they’re found. It shows the kinds of roles its genes might have, and how those jobs could be connected to things happening in the human body.

Now, researchers from UC San Diego and their colleagues have found that HPV DNA hybridizes with human DNA genes in oropharyngeal cancer cells, forming extrachromosomal circular DNA (ecDNA) that ...

Boundless Bio has formally launched with $46.4 million in funding from Arch Venture Partners and City Hill Ventures. The San Diego–based biotech firm hopes to prevent the proliferation of ...

Cancer therapies can eliminate specific tumors based on their genetic content. However, some cancer cells survive. How do they do it? Part of the answer lies in extrachromosomal DNA (ecDNA), an ace up ...

Extrachromosomal circular DNA (ecDNA) represents a distinct genomic entity that exists independent of the primary chromosomal structure. In cancer, ecDNA is recognised as a potent driver of oncogene ...

Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in tumor cells, it often carries cancer-promoting genes (oncogenes) and is ...