Understanding population genetic structure provides insight into the evolutionary past, present, and future of a species. In this study, we examine the rangewide population genetic structure of the ...

Endometrial carcinoma is the most frequent gynecological cancer. The disease-related death rate in FIGO stage II–IV is high (20–80% and higher), while in the ‘favorable’ early stage FIGO I, the death ...

Mice and rats are a fundamental component of drug discovery research. Standard outbred stocks and inbred strains of rodents are used extensively for drug safety and pharmacokinetic testing. Our ...

Improved CNS Control of Childhood Acute Lymphoblastic Leukemia Without Cranial Irradiation: St Jude Total Therapy Study 16 MSI status was available for 1,556 patients: 121 (7.8%) had MSI-high status; ...

MADISON, Wis.--(BUSINESS WIRE)--Researchers from Johns Hopkins University have shown that a new panel of long mononucleotide repeats (LMR) might offer advantages over traditional microsatellite ...

New diagnostic test for MSI in solid tumors can inform physicians on immuno-oncology therapies, and can guide treatment decisions for patients with Lynch-associated cancers LEIDEN, Netherlands & ...

Researchers from Johns Hopkins University have shown that a new panel of long mononucleotide repeats (LMR) might offer advantages over traditional microsatellite instability (MSI) detection methods in ...

This is a preview. Log in through your library . Abstract Inheritance of plant traits mainly depends upon nuclear genes, cytoplasmic factors and their interactions. In the present study, 32 ...

In this interview, News Med is talking to Gabriela Saldanha about DNA Fragmentation and Sanger Sequencing. What are Sanger sequencing and DNA-fragment analysis? Where are these analyses used? Sanger ...

Multiplex PCR is a difficult technique that allows amplification of two or more products in parallel in a single reaction tube. This technology was first described by Chamberlain et al., in 1988, and ...