Histology is one of the foundations of modern diagnostics. When physicians want to determine whether tissue is pathologically ...

A new holographic microscope allows scientists to see through the skull and image the brain. The new label-free deep-tissue imaging with the wave correction algorithm retrieves the fine neural network ...

Microscopy continues to transform the life sciences. Here are five recent breakthroughs made possible by the technique.

Until today, skin, brain, and all tissues of the human body were difficult to observe in detail with an optical microscope, since the contrast in the image was hindered by the high density of their ...

Both for research and medical purposes, researchers have spent decades pushing the limits of microscopy to produce ever deeper and sharper images of brain activity, not only in the cortex but also in ...

(A) Representative image of electron microscopy analysis of mouse acute pancreatitis tissues induced by cerulein treatment (for details, see Wang S et al 48). (B) An enlarged photograph from the boxed ...

Freshly dissected tissue (lower left) and its pathology-prepared slide with identified tumor regions by a pathologist (upper left), and a pseudo-color image of hyperspectral dark-field microscopy ...

A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a way to expand tissue before ...

Researchers have developed a new microscopy technology called decrowding expansion pathology (dExPath) to analyze brain tissue. By pulling proteins apart with dExPath, researchers can stain proteins ...

The researchers demonstrated the utility of their technique on a slice of a mouse brain, 200 microns (0.2 millimeters) in thickness. First, they made their tissue sample see-through using a tweaked ...