Model used to create a cellular ‘hologram’ of a mouse embryo could be used to visualize development in any species. Researchers have created the most detailed 3D cellular map yet of a mouse embryo, ...

Toward the goal of generating high-quality embryo models in vitro, this study establishes a stepwise protocol to derive trophectoderm-like cells from mouse extended pluripotent stem (EPS) cells. These ...

A stretch of viral DNA in the mouse genome gives cells in early-stage embryos the potential to become almost any cell type in ...

Infertility is a major healthcare concern. Understanding the molecular regulators governing fertilization, early embryonic ...

Researchers from the Wilmer Eye Institute, Johns Hopkins Medicine Center for Nanomedicine—which designs nanotechnology-based ...

Using CRISPR-based technologies, the MoDeL team introduces precise genetic modifications in mice, enabling researchers to uncover how mammalian genes maintain health and contribute to disease.

Scientists at the University of California, Santa Cruz (UCSC), used CRISPR to engineer cellular models of embryos that mimic what happens in the first few days after reproductive cells meet. These ...

Scientists are exploring ways to mimic the origins of human life without two fundamental components: sperm and egg. They are coaxing clusters of stem cells – programmable cells that can transform into ...

Embryo development starts when a single egg cell is fertilized and starts dividing continuously. Initially a chaotic cluster, it gradually evolves into a highly organized structure. Scientists have ...