Five mutational 'fingerprints' could help predict how visible tumors are to the immune system

Researchers from the HUN-REN Szeged Biological Research Centre and HCEMM have just published a new study suggesting that it's not simply the number of tumor mutations that matters for immunotherapy, ...
The Scientist

Distinct Mutations in the Same Gene Drive Cancer Differently

Mapping diverse mutations within a cancer hotspot revealed that distinct variants drive tumor growth to different extents, which could guide anticancer therapies.
Medscape

FDA OKs First Liquid Biopsy for Lung Cancer Mutation

The US Food and Drug Administration (FDA) today approved the first blood-based genetic test that can detect epidermal growth factor receptor (EGFR) gene mutations in non-small cell lung cancer ...
ascopubs.org

TP53 Y220C mutation in esophageal adenocarcinoma: A genomic landscape study.

CLDN18.2 IHC cutoff and efficacy of anti-CLDN18.2 therapy in gastric and gastroesophageal junction adenocarcinoma: A systematic review and meta-analysis. Selected genomic alterations in TP53 Y220C+ vs ...
News Medical on MSN

Five mutation patterns shape how cancers evade immunity

Cancer cells carry thousands of mutations, but not all mutations are created equal. Some make tumors highly visible to the ...