Researchers found a unique immune cell plays a key role in the chronic inflammation and scarring in the lungs and skin of people with scleroderma, or systemic sclerosis. After injecting mice with ...

Please provide your email address to receive an email when new articles are posted on . Rheumatologists are likely to be at the “forefront” of diagnosing scleroderma skin disorders and other ...

Please provide your email address to receive an email when new articles are posted on . The last 3 years of drug development in scleroderma have come to represent everything that ails the current ...

Epigenetic drugs that have shown promise in cancer trials significantly reduce scarring in the cells of patients with scleroderma, a new study shows. Results reveal that drugs that inhibit BRD4, known ...

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Scleroderma is a rare autoimmune disease involving an overproduction of the protein collagen. Linear scleroderma usually begins as a streak of hardened, waxy, discolored skin on the forehead, an arm, ...

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A team of researchers at the Medical University of South Carolina (MUSC) has found that the molecule lysyl oxidase (LOX) plays a number of important roles in promoting skin and organ fibrosis in ...

For the 300,000 Americans living with the immune disease scleroderma, better treatments can't come soon enough. The rare and sometimes fatal illness stiffens and scars tissue in organs like the lungs, ...

EXTENSIVE clinical data have been accumulated during recent years that support the view that scleroderma is a systemic disease. In addition to cutaneous involvement, which remains the cardinal ...