A $3 million donation from Big Nova supports NMDP programs that reduce barriers to blood stem cell transplants.

The answer is "it should be," says columnist. That way, sickle cell patients could receive the support that they need.

Standard treatments can significantly lower the risk of stroke in children with sickle cell anemia, according to a review of ...

Winter is one of columnist Michelle Harlan's favorite seasons, but having sickle cell disease means navigating this time of ...

A Phase 1b trial shows the higher dose of pociredir boosts fetal hemoglobin levels in adults with sickle cell disease.

Sickle cell disease (SCD) may be cured in some individuals by a stem cell transplant. There also are several approved therapies to help manage the condition and its related complications. Some of the ...

Supplementing with vitamin D for six months safely improved bone health and functional capacity in children and adolescents with sickle cell disease (SCD), a study finds. More studies are required to ...

For most of his 39 years, Charles Hough lived with extreme pain caused by sickle cell disease, which dramatically reduced blood flow throughout his body. But thanks to the gene therapy he received in ...

The Phase 1/2 CLIMB-SCD-121 trial (NCT03745287) is currently evaluating the safety and effectiveness of a single infusion of CTX001 in adults up to age 35 with severe SCD. Two patients have been dosed ...

A newly designed viral vector — the vehicle that delivers a gene therapy to a patient’s cells — for use in sickle cell anemia is more efficient than earlier vectors at introducing healthy copies of ...

Using tocilizumab off-label in four young adults with sickle cell disease (SCD) who developed hyperhemolysis syndrome as a complication of a blood transfusion stopped the premature destruction of red ...

On Dec. 8, the U.S. Food and Drug Administration (FDA) approved two cell-based gene therapies for sickle cell disease (SCD), a groundbreaking decision that now offers patients more than one ...