Activating two somatostatin receptors enhances amyloid beta breakdown and improves memory in models of Alzheimer’s disease. Scientists at Karolinska Institutet in Sweden and the RIKEN Center for Brain ...

Opioid receptors are a subset of G protein–coupled receptors (GPCRs). These membrane proteins transmit signals into the cell ...

Northeastern University researchers have made a breakthrough drug discovery, developing the first synthetic endogenous ...

GPCRs (G protein-coupled receptors), also known as 7 transmembrane domain receptors, are the largest receptor family in the human genome, with ≈800 members. GPCRs regulate nearly every aspect of human ...

While the COVID pandemic has thankfully been over for some time now, there is still a considerable number of people in the world (about 400 million) suffering from long COVID. Long COVID is a chronic ...

Bitter taste receptors are not only expressed in oral cavity cells but also in the gastrointestinal lining. To understand the diverse functions of these receptors, understanding the structure is ...

A leading Chinese drug developer has moved a step closer to joining multinationals in the booming market for weight-loss medications. Two months after listing its shares in Hong Kong, Jiangsu Hengrui ...

Department of Pharmacology and Therapeutics, University of Florida, Gainesville, Florida 32610, United States Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, ...

The brain’s cerebellum plays a key role in coordinating movement, balance, and cognition. Injury to the cerebellum can have a profound impact on basic motor skills, such as sitting, standing, and ...

Summary: For the first time, scientists have mapped the 3D structure of the human sweet taste receptor, offering critical insights into how we perceive sweetness and why we crave sugar. This detailed ...